I have recently over the past few months went from being dependent on oxycodone to having an addiction to it. I over use because of the addiction and want off all narcotics at this time. I am looking for any alternatives to narcotics to treat knee pain, fibromyalgia and Restless Leg Syndrome. PLEASE HELP I am desperate for alternatives. I have tried heat, ice, NSAID’S, physical therapy and numerous braces for knee and back pain and currently take REQUIP and Valium for RLS.

The aches and pains in her muscles just would not stop. After the car accident, it seemed like everything was going downhill. First she lost her job, then her boyfriend. Sleep hardly ever comes and if it does, the pain and tightness in her shoulders and neck wake her up. After countless visits to a myriad of specialists, she finally got a diagnosis. She thought that she was going crazy, but the rheumatologist said she had fibromyalgia. Learn about this mysterious ailment, the signs and symptoms, the latest theory on the cause, and some treatment options in this article. For an in-depth look at diet and supplementation that may benefit fibromyalgia see the article “Nutritional Strategies For Fibromyalgia.”

Complicated Syndrome

Fibromyalgia (FM) literally means pain in the fibrous connective tissue that surrounds joints, typically the muscle and the tendon that attaches the muscle to the bone. It isn’t a disease, but rather a syndrome, which is a collection of signs and symptoms that occur together. It is a form of soft tissue rheumatism. The American College of Rheumatology defines FM as widespread pain present for at least three months in combination with tenderness at 11 or more of 18 specific tender point sites. FM used to be called fibrositis, but that erroneous definition meant an inflammatory condition was present, and that is not the case. Because of the difficulty in diagnosing FM and the similarities that FM has to other diseases, many people are not properly diagnosed, or the diagnosis takes much time and effort. Since FM affects 2% of the United States population, with a breakdown of 3.4% in women and 0.5% in men, this is not a rare syndrome.

Signs and Symptoms

FM patients usually report that they “hurt all over” and describe their pain as stabbing, aching, or nagging. They also describe feelings of stiffness, especially upon waking up. Pain with palpation is found in 11 of 18 specific points that have been identified around the body. FM patients can suffer from fatigue, sleep disturbances, headaches, abdominal pain, bloating, constipation, diarrhea, bladder urgency and frequency, and skin sensitivity. FM seems to occur in a vicious circle. The lack of sleep leads to sore muscles and fatigue, which leads to less participation in physical activity, which results in depression and further deconditioned muscles, which leads to more pain, which leads to less sleep.

The Central Nervous System Theory

Many researchers now believe that the central nervous system (CNS) plays a large role in the development of this syndrome. The central nervous system is composed of the spinal cord and brain. What investigators think is that an event, either emotionally or physically traumatic, leads to hyperactivity in the CNS. This hyperactivity leads to sleep disturbances, like the increased number of awakenings found in FM patients. The hyperactivity also affects the ratio of excitatory to inhibitory neurotransmitters. Neurotransmitters are chemical messengers that communicate between nerves. In FM, there appears to be larger concentrations of excitatory neurotransmitters (like Substance P) and lower concentrations of inhibitory neurotransmitters (like serotonin). This irregular ratio causes the pain amplification in FM patients. FM patients’ pain perception is normal, but their sensitivity to pain is increased and their tolerance of pain is decreased. The CNS hyperactivity can then lead to problems involving all bodily systems, which explains the seemingly unrelated symptoms of FM. There is even reason to believe that FM may have a genetic component.

FM Management

A combination of medication, cognitive behavior therapy, relaxation techniques, exercise, and education is recommended as treatment for FM. Medications that help promote sleep and relaxation have been used, but studies have met with mixed results. Nonsteroidal anti-inflammatory drugs (NSAIDs) aren’t more effective than placebos and corticosteriod injections make FM symptoms worse. Trigger point injections using a local anesthetic can be helpful, but only have temporary effects, and the authors of one study that showed symptom improvement still recommended other forms of treatment. Only one high quality study suggests that real acupuncture is more effective than sham acupuncture. Cognitive behavior therapy, which involves learning affective coping strategies, and stress-reduction programs were proven to be successful in the long term treatment of FM.

Exercise programs that emphasize cardiovascular fitness seem to be the tool for breaking the circle of pain. FM patients are deconditioned from avoiding exercise. This can lead to further pain from shortened and tight muscles. Many doctors recommend a balanced program of flexibility, gentle strengthening, and aerobic conditioning. Exercise should be thought of as health training, not sports training. The intensity and duration should begin slowly, but become a part of the FM patient’s lifestyle. Pool exercises are a good place to start with a gradual progression to land exercises. Physical therapists can help design exercise and stretching programs. The Arthritis Foundation recommends also learning progressive muscle relaxation techniques in addition to exercise and stretching.

The Good News

FM is not a life threatening disease, nor is it physically deforming. Symptoms do not usually get worse and may be lessened with appropriate interventions. Although researchers are still working on a complete explanation for the syndrome, progress is advancing rapidly. Without a definitive treatment for every FM patient, an individualized approach and experimentation with different methods should be utilized. In a study of FM patients who still had symptoms after ten years of onset, 66% of patients reported that their symptoms were a little or a lot better, 55% said they felt well or very well, and only 7% felt they were doing poorly. Of course, education about the syndrome is the first step to understanding and beginning a treatment program. For more information, visit the American College of Rheumatology website at http://www.rheumatology.org or The Arthritis Foundation website at http://www.arthritis.org. You can call Fibromyalgia Alliance of America, Inc., (614) 457-4222 and Fibromyalgia Network info line: (520) 290-5508. A newsgroup devoted to fibromyalgia can be found at alt.med.fibromyalgia.

References upon request.

By: Thomas Incledon

About the Author:

What is the understanding of fibromyalgia?

Dr. Chad S. Boomershine shares a technique to help rheumatologists take the pain out of treating fibromyalgia.

I have tried every SSRI, Tramadol, and Darvocet and alot of drugs that I cant even remember at the moment. I am currently on Lortab but it just stopped working. I have heard about Gabapentin and Guaifenesin and I will be trying them but I need something for my overwhelming pain. I am assuming that I will end up taking Percocet next, but what happens after that? My body keeps building up tolerances very quickly, is there any way to stop that from happening? Is there anyone out there who has gone through this before (the escalation of pain meds for FSM or CFIDS)?
An SSRI is an antidepressant, specifically the type they give to people in chronic pain. It took me 5 years of medical tests to get the diagnosis of Fibromyalgia. I am still getting every test done that I can but every specialist I have seen has found nothing wrong with me.
I have taken Lyrica and Cymbalta, along with several other anti-depressants (Lexapro, Wellbutrin, etc) that I took because in the early years, before my pain was severe, doctors just kept trying to tell me I was depressed, even though I wasn’t emotionally unhappy at all. I’m pretty sure I have taken every drug that is associated with FMS except Gabapentin and Guaifenesin. At least so far.
Heat helps alot definitely, but cold does help too for my head sometimes when I get non-migraine headaches.
I want to thank everyone who advised against Gabapentin because I am in real pain, I have faced alot of negativity and alot of accusations that I am making things up so your remarks are very validating. I didn’t know that Gabapentin was only helpful for people who just think they are in pain. Its nice to know because it is something my doctor has never suggested, which means he knows that I am in real pain. It might sound silly, but that makes me really happy.

i’ve had many accidents in my life. i’ve injured many areas of my body and then got diagnosed with both chronic pain disorder as well as “borderline” fibromyalgia. one of the medications i have taken for so long is amitriptilyne (elevil), one 25 mg./night.

in the past 6 to 9 months, i have been experiencing, daily, a pain all over my body (but not in my torso itself) whereby it feels like the fascia that holds the musles and tendons on the bones aches. what is this condition? what is done to treat it? my doctor already doubled the dose of elevil that i take each night. it only helps a little bit. i do NOT have arthritis and do not need a rheumatologist. what else could this be?

I was diagnosed with fibromyalgia about a year ago. I have 16 of the 18 tender points, and all the **** that comes with fibromyalgia. I have 2 spots that have always hurt me the most, and theyre not on any of the typical tenderspots. Does anyone else have severe tenderspots thats not typical for fibromyalgia? If not, could it be that the diagnosis of my fibromyalgia is wrong???

Would like to chat with someone who has fibromyalgia. Do they have a heightened sense of smell??Everything smells different or horrible.Is this part of the illness??

I am a twenty-one year old, female, diagnosed with Fibromyalgia, Chronic Fatigue Syndrome, and REM sleep disorder. My Dr. is now questioning the possibility of Myofascial Pain Syndrome… In the past I have tried physical therapy, acupuncture and multiple prescribed medications both for the pain and the sleep problems… none have been quite sufficient or cost effective, in the long run… any suggestions?

I have hyperreflexia, and tremors in my fingers does anyone one else have this also? And also can other symptoms show up later with fibromyalgia?